Endocrine Abstracts

Background: Diabetic neuropathy (DN) is a major complication of diabetes, affecting one in three people with diabetes. The presence of peripheral neuropathy increases their risks of developing foot ulceration and subsequent necrosis that results in lower limb amputation. Good diabetes control helps to lower the risk of diabetic complications, which can be accelerated by advanced glycation end-products (AGEs) or alcohol consumption. AGEs are heterogeneous group of molecules, th...